Turn-key data solutions for genetic research in animals and plants

Modern genetic analysis in animals and plants presents researchers with the opportunity for breakthroughs - and the challenge of overwhelming amounts of data. This unprecedented bulk of data, and the management that it requires, diverts resources and focus from the more scientifically relevant tasks. Our solutions are helping the leading research teams worldwide in various human, animal and plant genetic data management and analysis projects.

BC|GENE and BC|SNP solutions are database platforms, integrating sequence/variation and high-density SNP genotype data with phenotypes, pedigrees and maps to create productive data analysis pipelines. They simplify genetic data management, automate tedious data management tasks and facilitate efficient analysis workflows.

Benefits for researchers:

• Efficient data transfer and tracking of changes
• Automation of tedious data management and formatting tasks
• User-friendly interface for the analysis methods of your choice
• More efficient, parallel data analysis
• Assistance and expertise in data management and analysis
• Regular updates, support for new data types and genetic analysis programs
• Scalability from small studies to the largest of studies
• Cost-effective and short deployment times

Getting the most from your valuable research data

BC|GENE and BC|SNP database platforms have a secure and user-friendly web browser interface. The easy-to-use interface facilitates the management and sharing of data and results within a research team and between research collaborators. Additionally, secure remote access enables working from external locations and can be used for multi-center data collection and exchange.

Team members can have different user profiles as well as distinct rights to access data. Comprehensive log files cover all data entries and modifications and system access allowing the tracing of every variable's change history.

Efficient, flexible and secure data analysis

Through the web browser interface, you can combine data from multiple sources, filter subjects or markers based on various criteria, such as quality, location, and previous analysis results. Data analysis is further enhanced by automated procedures for data format conversions and speed optimized analysis workflows.

BC|SNP Suite offers special functions and features to tackle the challenge of managing massive amounts of data. An advanced built-in queue system interleaves large database transactions and calculation tasks, enabling efficient use of calculation capacity. Analysis runs containing a large number of markers can be automatically divided into multiple smaller tasks, the results of which the system then collates into one file. Local servers, institute calculating cluster or cloud computing can be used for data analysis.

BC|GENE and BC|SNP data management solutions facilitate the use of the best analysis programs developed in academia. Additional analysis programs or custom applications can be integrated using the system's Application Programming Interface (API).

Supported analysis methods (among others):

• Data quality checks
• Association and linkage disequilibrium
• NGS and GWAS data management and analysis
• Population stratification
• Haplotyping
• Scripting (R, SAS®, Perl etc.)
• Imputing (in-silico-genotyping)
• Data exports to SPSS®, STATA®, Excel®, SAS®
• Gateway to genome browsers
• Linkage analysis
• TDT and pedigree based association
• Epistasis
• ODBC access