Technical White Papers

Using cloud computing for parallel analysis of genome-wide datasets (PDF 229 kb)

The BC|SNPmax database platform supports parallelization of genetic analysis, also in a cloud computing environment. The following white paper describes some of the challenges in using cloud computing for parallel genetic analysis and the feasibility of cloud computing for distributed genetic analyses.

Entering the era of Genome-Wide Association Study 2.0 (PDF 118 kb)

When using reference data from the correct population, it is possible to accurately impute a large number of new SNPs for each subject. These new SNPs may be better surrogates than SNPs in the chip, or even causal variants, giving superior results in association analysis. Some experts even recommend re-analyzing all the performed genome-wide association studies with this new method. The following white paper summarizes the GWAS 2.0 workflow using BC|SNPmax.