OMOP harmonization and federated analytics for oncology

Executive summary

The ONCOVALUE consortium, a collaborative effort of cancer institutes and industrial partners, is dedicated to implementing value-based oncology care. Central to its mission are the localized harmonization of high-quality Real-World Data (RWD) to facilitate the development of federated analytical frameworks for the assessment the effectiveness of novel cancer therapies across multiple institutions as well as other HTA analysis.

Process

Partner sites will harmonize oncology data using OMOP CDM and standard procedures. Consistent data formatting and harmonization ensure comparability across collaboration partners, which is vital for downstream analytics.

Outcome

OMOP CDM unifies clinical data from diverse sources for federated queries and analyses. BCP enables data-driven insights into novel cancer therapies, evaluation of their real-life effectiveness and support of evidence-based decision-making in oncology. This lays the foundation for large scale trials and fosters collaboration towards improving cancer care outcomes globally.